Ipamorelin
5 mg
Selective ghrelin receptor agonist pentapeptide, 5 mg per vial.
- CAS
- 170851-70-4
- Sequence
- Aib-His-D-2-Nal-D-Phe-Lys-NH2
- Storage
- Refrigerated
Comparison
Ipamorelin vs Tesamorelin
Both are studied in growth hormone research, and they act on opposite ends of the same axis. Confusing them is common because the outcome measured is often similar; the mechanism is not.
What is the difference between ipamorelin and tesamorelin?
They are the two separate arms of the growth hormone axis, not competitors. Ipamorelin acts at the ghrelin receptor and is the standard control precisely because it does so little else. Tesamorelin acts at the GHRH receptor and carries protease resistance, and its literature is concentrated in visceral adipose research rather than growth signalling generally. A protocol pairing one of each is common, because that is how the two arms get studied together.
Side by side
| Property | Ipamorelin | Tesamorelin |
|---|---|---|
| Receptor | Ghrelin receptor (GHSR) | GHRH receptor |
| Class | Growth hormone releasing peptide (GHRP) | GHRH analogue |
| Length | Pentapeptide | 44 residues, a stabilised full GHRH sequence |
| Molar mass | 711.86 g/mol | 5135.8 g/mol |
| Selectivity | The most selective GHRP; minimal cortisol or prolactin involvement | Acts only at the GHRH receptor |
| Research emphasis | Isolating ghrelin receptor activity as a clean control | Visceral adipose tissue models specifically |
| Price | $46 for 5 mg | $96 for 5 mg |
| Price | $46.00 · 5 mg | $96.00 · 5 mg |
Both compounds
Tesamorelin
5 mg
Stabilised GHRH analogue, 5 mg per vial.
- CAS
- 218949-48-5
- Storage
- Refrigerated
Questions
Do ipamorelin and tesamorelin work the same way?
No. Ipamorelin acts at the ghrelin receptor and tesamorelin at the GHRH receptor. These are the two distinct arms of the growth hormone axis, which is why blends pairing a GHRP with a GHRH analogue are common.
Why is tesamorelin more expensive?
It is a far larger molecule. Tesamorelin is a 44-residue stabilised GHRH sequence at 5135.8 g/mol against ipamorelin at 711.86, and synthesis cost scales with peptide length.
Can they be studied together?
Frequently, since they engage different receptors on the same axis. The CJC-1295 and ipamorelin blend follows the same GHRH-plus-GHRP logic with a different GHRH analogue.
Other comparisons
- BPC-157 vs TB-500 What is the difference between BPC-157 and TB-500?
- Semaglutide vs Tirzepatide What is the difference between semaglutide and tirzepatide?
- Tirzepatide vs Retatrutide What is the difference between tirzepatide and retatrutide?
- CJC-1295 with DAC vs without DAC What is the difference between CJC-1295 with and without DAC?
- IGF-1 LR3 vs IGF-1 DES What is the difference between IGF-1 LR3 and IGF-1 DES?
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