CJC-1295 DAC
5 mg
GHRH analogue with drug affinity complex, 5 mg per vial.
- Storage
- Refrigerated
Comparison
CJC-1295 with DAC vs without DAC
The same GHRH analogue in two forms. The drug affinity complex is the only difference, and it changes the exposure profile from a pulse measured in minutes to sustained elevation measured in days.
What is the difference between CJC-1295 with and without DAC?
This is a choice about exposure pattern, not about strength. The DAC form holds levels elevated continuously, which suits research into sustained receptor occupancy. The no-DAC form produces a discrete pulse that resembles the body's own release pattern, which is what makes it the right one when pulsatility itself is what is being studied.
Side by side
| Property | CJC-1295 DAC | CJC-1295 |
|---|---|---|
| Drug affinity complex | Present, a maleimidoproprionic acid group | Absent |
| Albumin binding | Binds serum albumin | Does not bind |
| Exposure profile | Sustained elevation over days | Short pulse over minutes |
| Molar mass | 3647.2 g/mol | 3367.9 g/mol |
| Also called | CJC-1295 DAC, long-acting GHRH | Modified GRF 1-29, mod GRF |
| Studied where | Sustained receptor exposure is the variable | Pulsatility is the variable |
| Price | $65.00 · 5 mg | $52.00 · 5 mg |
Both compounds
CJC-1295
5 mg
Modified GRF 1-29 without drug affinity complex, 5 mg per vial.
- Storage
- Refrigerated
Questions
What does DAC stand for?
Drug affinity complex. It is a maleimidoproprionic acid group that binds serum albumin, which extends circulating half-life from minutes to days.
Is CJC-1295 without DAC the same as Modified GRF 1-29?
Yes. The two names describe the same molecule: a GHRH 1-29 fragment with four amino acid substitutions for stability and no albumin-binding complex attached.
Why would a shorter exposure be preferred?
Natural growth hormone release is pulsatile rather than continuous. Where a research design needs to preserve that pattern, sustained elevation would confound the result, so the no-DAC form is used.
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All products listed are sold strictly for in-vitro laboratory research and analytical use. They are not drugs, foods, cosmetics or medical devices, and are not intended to diagnose, treat, cure or prevent any disease.